The Union government has sent an advisory to states on HFMD (Hand Foot & Mouth Disease), commonly known as Tomato Flu, stating that its a self-limiting illness targeting mostly young children aged 1–10 years and immune-compromised adults, and no specific drug exists to treat it. Further, the advisory mentioned that although the Tomato Flu virus shows symptoms similar to other viral infections, however, the virus is not at all related to SARS-CoV-2, monkeypox, dengue, and/or chikungunya. The best method of prevention is the maintenance of proper hygiene and sanitization of the surrounding areas.

Tomato flu was first identified in Kollam, Kerala on May 6, 2022. As of July 26, over 82 children younger than 5 years old with the infection have been reported by government hospitals. Additionally, 26 children (aged 1–9 years) were reported as having the disease in Odisha by RMRC Bhubaneswar. This endemic viral illness triggered an alert in the neighboring states of  Kerala, i.e., Tamil Nadu and Karnataka.

Tomato Flu is a viral disease with its name coming from the main symptom of the disease, the tomato-shaped blisters on several body parts. The blisters start as small red blisters and resemble tomatoes when they enlarge. The Union Ministry stated that the primary symptoms observed in children with tomato flu are fever, rashes, and pain in the joints. They added that tomato flu is a self-limiting infectious disease as the signs and symptoms resolve after a few days. Infants and young children are also prone to this infection through the use of nappies, touching unclean surfaces, as well as putting things directly into their mouths. 

There are no disease-specific medications available for HFMD, but the treatment method is similar to other viral infections, i.e., isolation, rest, plenty of fluids, and a hot water sponge for relief of irritation and rashes. Supportive therapy of paracetamol for fever and body aches and other symptomatic treatments are required. Currently, there are no antiviral drugs or vaccines available to treat or prevent tomato flu. Further follow-up and monitoring for serious outcomes and sequelae are needed to better understand to come up with potential treatment protocols.